Bokt.nl

[***] schreef:

....Edit; zit nog te denken.. moest hij echt last hebben van afvalstoffen, kan dat ook dingen als ZE veroorzaken ofzo? (dat die stoffen zich vastzetten en die mugjes aantrekken of iets dergelijks?). Want dan is het zeker wel de moeite waard om verder te bekijken natuurlijk..

Citaat:

Madigan has identified a correlation of gender to this behavior, finding 66-75% of cases are geldings. "In some studies," he reports, "90% are geldings. The prototype is 9 to 11 years old, although the age range is wide."

Madigan says there is a rise in reproductive hormones called gonadotropins in the spring, and this is normally associated with the breeding season typical of horses. He explains, "This surge occurs as days lengthen. Geldings have no testosterone feedback, so they have higher levels of gonadotropins, like FSH (follicle-stimulating hormone) and LH (luteinizing hormone), for a period of time."

In evaluating if these particular reproductive hormones play a role in the pathophysiology of trigeminal nerve irritation, he describes research done on ferrets that were found to have an amplified adrenal response following neutering procedures--the researchers identified the presence of LH receptors on the adrenal glands of these neutered animals.

Madigan says, "This demonstrates that reproductive trophic (pertaining to a nutritive effect on or quality of cellular activity) hormones can have target tissues outside the reproductive tract, especially when levels of gonadotropins are higher due to lack of normal feedback, similar to what occurs in testosterone-deficient geldings."

How do gonadotropins influence the trigeminal nerve? Madigan explains, "The hormones seem to affect some part of the trigeminal ganglia, altering its chemistry and rendering it unstable. (Ganglia provide relay points and connections between nerves.) As normal sensory 'traffic' comes into the trigeminal ganglia, then additional triggers like light, sound, smell, or exercise may stimulate this nerve to 'fire.'

"The horse then receives neuropathic pain such as burning, itching, tingling, or electriclike sensations, any of which are manifestations of horses with headshaking," he adds.

A New Zealand mare provided evidence to the role of gonadotropins. Madigan describes the case: "In the spring, exam of a 4-year-old headshaking mare found small ovaries along with sky-high LH levels. She was given an anti-GnRH (gonadotropin-releasing-hormone) vaccine (Equity) licensed in New Zealand; this dropped her LH levels and the headshaking behavior went away, and stayed away."

By altering gondadotropin access to the trigeminal nerve, he says the adverse behavior can be modified in other horses, too. Madigan notes, "There have been cases of headshaking in stallions, but 50% have responded to gonadotropin therapy "

drunny schreef:

Nieuw...! voor het eerst in zijn hele leven (want ik heb hem al als veulen, zelf gefokt) heeft hij zich als een poesje uitgerekt. vandaag 2x in 10 min tijd.
voor mijn gevoel zit hij veel beter in zijn vel dan ooit tevoren, hij heeft nog wel jeuk aan zijn neus en shud nog regelmatig maar met rijden is het bijna helemaal weg.
hopelijk zitten we nu in de laatste fase .....