Moderators: Mjetterd, Dani, ynskek, Ladybird, xingridx, Polly, Hanmar
Citaat:She recommended interferon alpha 2b, 5-FU, or MMC to treat these squamous lesions.
Source: https://www.eyeworld.org/
bron: https://eyewiki.aao.org/Ocular_Surface_ ... _neoplasiaCitaat:Immunosuppression/ HIV
In Africa, studies have shown an HIV infection rate as high as 79% in patients with OSSN compared to 14% in the general population.[9] In the United States, a study done at Bascom Palmer Eye Institute found that OSSN may be a possible marker for undiagnosed HIV. [5] The study found that half of patients diagnosed with OSSN under the age of 50 were seropositive for the virus.[5]
Human papillomavirus (HPV)
The association of HPV with OSSN remains unclear. Although some studies have shown a clear association of OSSN with HPV, other studies have not. [10] [11]Whereas HPV 6,8, and 11 have been linked with benign conjunctival epithelial lesions, HPV 16 and 18 have been associated with malignant neoplastic lesions.[1] However, HPV status does not appear to correlate to treatment response.
Mutation or deletions of tumor suppressor gene p53.
Mutations of p53, a tumor suppressor gene, are thought to be the most common genetic anomalies in human malignancies. [1] Some have hypothesized that HPV or UV-B may alter p53, resulting in the development of OSSN in susceptible individuals.[7]
Hannanas schreef:Citaat:She recommended interferon alpha 2b, 5-FU, or MMC to treat these squamous lesions.
Source: https://www.eyeworld.org/
Kan je eigen oogarts je die MMC (mitomycine) niet geven?
Las ook ergens dat dit in verband wordt gebracht met HPV en HIV. Hebben ze beide gecontroleerd bij je?bron: https://eyewiki.aao.org/Ocular_Surface_ ... _neoplasiaCitaat:Immunosuppression/ HIV
In Africa, studies have shown an HIV infection rate as high as 79% in patients with OSSN compared to 14% in the general population.[9] In the United States, a study done at Bascom Palmer Eye Institute found that OSSN may be a possible marker for undiagnosed HIV. [5] The study found that half of patients diagnosed with OSSN under the age of 50 were seropositive for the virus.[5]
Human papillomavirus (HPV)
The association of HPV with OSSN remains unclear. Although some studies have shown a clear association of OSSN with HPV, other studies have not. [10] [11]Whereas HPV 6,8, and 11 have been linked with benign conjunctival epithelial lesions, HPV 16 and 18 have been associated with malignant neoplastic lesions.[1] However, HPV status does not appear to correlate to treatment response.
Mutation or deletions of tumor suppressor gene p53.
Mutations of p53, a tumor suppressor gene, are thought to be the most common genetic anomalies in human malignancies. [1] Some have hypothesized that HPV or UV-B may alter p53, resulting in the development of OSSN in susceptible individuals.[7]
Polly schreef:Voor pcm is een maahbeschermer niet nodig maar voor de ibuprofen zou ik die zeker wel nemen.
4dd1000mg mag alleen kortdurend, gezien het feit dat dit al een langdurige kwestie is zou ik voor 3x 1000 gaan.